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Role of GPER in estrogen-dependent nitric oxide formation and vasodilation

Estrogens are potent regulators of vascular tone, yet underlying receptor- and ligand-specific signaling pathways remain poorly characterized. The primary physiological estrogen 17β-estradiol (E2), a non-selective agonist of classical nuclear estrogen receptors (ERα and ERβ) as well as the G protein...

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Détails bibliographiques
Publié dans:J Steroid Biochem Mol Biol
Auteurs principaux: Fredette, Natalie C., Meyer, Matthias R., Prossnitz, Eric R.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694388/
https://ncbi.nlm.nih.gov/pubmed/28529128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2017.05.006
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