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Role of GPER in estrogen-dependent nitric oxide formation and vasodilation

Estrogens are potent regulators of vascular tone, yet underlying receptor- and ligand-specific signaling pathways remain poorly characterized. The primary physiological estrogen 17β-estradiol (E2), a non-selective agonist of classical nuclear estrogen receptors (ERα and ERβ) as well as the G protein...

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Detalles Bibliográficos
Publicado en:J Steroid Biochem Mol Biol
Autores principales: Fredette, Natalie C., Meyer, Matthias R., Prossnitz, Eric R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694388/
https://ncbi.nlm.nih.gov/pubmed/28529128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2017.05.006
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