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Obligatory role for GPER in cardiovascular aging and disease

Pharmacological activation of the heptahelical G protein-coupled receptor GPER by selective ligands counteracts multiple aspects of cardiovascular disease. We thus expected that genetic deletion or pharmacological inhibition of GPER would further aggravate such disease states, particularly with age....

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Meyer, Matthias R., Fredette, Natalie C., Daniel, Christoph, Sharma, Geetanjali, Amann, Kerstin, Arterburn, Jeffrey B., Barton, Matthias, Prossnitz, Eric R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124501/
https://ncbi.nlm.nih.gov/pubmed/27803283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aag0240
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