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Obligatory role for GPER in cardiovascular aging and disease
Pharmacological activation of the heptahelical G protein-coupled receptor GPER by selective ligands counteracts multiple aspects of cardiovascular disease. We thus expected that genetic deletion or pharmacological inhibition of GPER would further aggravate such disease states, particularly with age....
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| Veröffentlicht in: | Sci Signal |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5124501/ https://ncbi.nlm.nih.gov/pubmed/27803283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aag0240 |
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