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Obligatory role for GPER in cardiovascular aging and disease

Pharmacological activation of the heptahelical G protein-coupled receptor GPER by selective ligands counteracts multiple aspects of cardiovascular disease. We thus expected that genetic deletion or pharmacological inhibition of GPER would further aggravate such disease states, particularly with age....

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Bibliografski detalji
Izdano u:Sci Signal
Glavni autori: Meyer, Matthias R., Fredette, Natalie C., Daniel, Christoph, Sharma, Geetanjali, Amann, Kerstin, Arterburn, Jeffrey B., Barton, Matthias, Prossnitz, Eric R.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124501/
https://ncbi.nlm.nih.gov/pubmed/27803283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aag0240
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