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Antibody Heavy Chain Variable Domains of Different Germline Gene Origins Diversify through Different Paths
B cells produce antibodies, key effector molecules in health and disease. They mature their properties, including their affinity for antigen, through hypermutation events; processes that involve, e.g., base substitution, codon insertion and deletion, often in association with an isotype switch. Inve...
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| Publié dans: | Front Immunol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5694033/ https://ncbi.nlm.nih.gov/pubmed/29180996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01433 |
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