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Poorly Expressed Alleles of Several Human Immunoglobulin Heavy Chain Variable Genes are Common in the Human Population

Extensive diversity has been identified in the human heavy chain immunoglobulin locus, including allelic variation, gene duplication, and insertion/deletion events. Several genes have been suggested to be deleted in many haplotypes. Such findings have commonly been based on inference of the germline...

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Pubblicato in:Front Immunol
Autore principale: Ohlin, Mats
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943739/
https://ncbi.nlm.nih.gov/pubmed/33717051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.603980
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