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Poorly Expressed Alleles of Several Human Immunoglobulin Heavy Chain Variable Genes are Common in the Human Population

Extensive diversity has been identified in the human heavy chain immunoglobulin locus, including allelic variation, gene duplication, and insertion/deletion events. Several genes have been suggested to be deleted in many haplotypes. Such findings have commonly been based on inference of the germline...

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Publicado en:Front Immunol
Autor principal: Ohlin, Mats
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943739/
https://ncbi.nlm.nih.gov/pubmed/33717051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.603980
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