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Decoding HIV resistance: from genotype to therapy
Genetic variation in HIV poses a major challenge for prevention and treatment of the AIDS pandemic. Resistance occurs by mutations in the target proteins that lower affinity for the drug or alter the protein dynamics, thereby enabling viral replication in the presence of the drug. Due to the prevale...
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| Publicat a: | Future Med Chem |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Future Science Ltd
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5694023/ https://ncbi.nlm.nih.gov/pubmed/28791894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2017-0048 |
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