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Whole exome sequencing of wild-derived inbred strains of mice improves power to link phenotype and genotype

The house mouse is a powerful model to dissect the genetic basis of phenotypic variation, and serves as a model to study human diseases. Despite a wealth of discoveries, most classical laboratory strains have captured only a small fraction of genetic variation known to segregate in their wild progen...

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Dettagli Bibliografici
Pubblicato in:Mamm Genome
Autori principali: Chang, Peter L., Kopania, Emily, Keeble, Sara, Sarver, Brice, Larson, Erica, Orth, Annie, Belkhir, Khalid, Boursot, Pierre, Bonhomme, François, Good, Jeffrey M., Dean, Matthew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693759/
https://ncbi.nlm.nih.gov/pubmed/28819774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-017-9704-9
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