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A new nonradioactive deoxyhypusine synthase assay adaptable to high throughput screening
Deoxyhypusine synthase (DHS) catalyzes the post-translational modification of eukaryotic translation factor 5A (eIF5A) by the polyamine, spermidine, that converts one specific lysine residue to deoxyhypusine [N(ε)-4-aminobutyl(lysine)], which is subsequently hydroxylated to hypusine [N(ε)-4-amino-2-...
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| Udgivet i: | Amino Acids |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693660/ https://ncbi.nlm.nih.gov/pubmed/28819816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-017-2477-3 |
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