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Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development

The eukaryotic initiation factor 5A (eIF5A) contains a polyamine-derived amino acid, hypusine [N(ε)-(4-amino-2-hydroxybutyl)lysine]. Hypusine is formed post-translationally by the addition of the 4-aminobutyl moiety from the polyamine spermidine to a specific lysine residue, catalyzed by deoxyhypusi...

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Hlavní autoři: Nishimura, Kazuhiro, Lee, Seung Bum, Park, Jong Hwan, Park, Myung Hee
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220921/
https://ncbi.nlm.nih.gov/pubmed/21850436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-011-0986-z
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