Peripheral immune tolerance alleviates the intracranial lipopolysaccharide injection-induced neuroinflammation and protects the dopaminergic neurons from neuroinflammation-related neurotoxicity

BACKGROUND: Neuroinflammation plays a critical role in the onset and development of neurodegeneration disorders such as Parkinson’s disease. The immune activities of the central nervous system are profoundly affected by peripheral immune activities. Immune tolerance refers to the unresponsiveness of...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Liu, Yang, Xie, Xin, Xia, Li-Ping, Lv, Hong, Lou, Fan, Ren, Yan, He, Zhi-Yi, Luo, Xiao-Guang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693474/
https://ncbi.nlm.nih.gov/pubmed/29145874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0994-3
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