Peripheral immune tolerance alleviates the intracranial lipopolysaccharide injection-induced neuroinflammation and protects the dopaminergic neurons from neuroinflammation-related neurotoxicity

BACKGROUND: Neuroinflammation plays a critical role in the onset and development of neurodegeneration disorders such as Parkinson’s disease. The immune activities of the central nervous system are profoundly affected by peripheral immune activities. Immune tolerance refers to the unresponsiveness of...

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Publicat a:J Neuroinflammation
Autors principals: Liu, Yang, Xie, Xin, Xia, Li-Ping, Lv, Hong, Lou, Fan, Ren, Yan, He, Zhi-Yi, Luo, Xiao-Guang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693474/
https://ncbi.nlm.nih.gov/pubmed/29145874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0994-3
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