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DDIS-22. ANTI-DEPRESSANT, SSRI IDENTIFIED BY DRUG REPOSITIONING SYSTEM, BLOCKED GLIOBLASTOMA INVASION WITH TARGETING TO INHIBIT ACTIN POLYMERIZATION
Invasion of Glioblastoma (GBM) cells into normal brain is the major cause of poor prognosis and requires dynamic reorganization of the actin cytoskeleton, which includes lamellipodial protrusions, focal adhesions, and stress fibers at the leading edge of GBM cells. Therefore, we hypothesized that in...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693191/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.257 |
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