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DDIS-01. NEW DRUG DISCOVERY WITH DRUG RE-POSITIONING SYSTEM TOWARD GBM TREATMENT

INTRODUCTION: Invasion of Glioblastoma (GBM) cells into normal brain is the major cause of poor prognosis and requires dynamic reorganization of the actin cytoskeleton, which includes lamellipodial protrusions, focal adhesions, and stress fibers at the leading edge of GBM cells. Therefore, we hypoth...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Michiue, Hiroyuki, Tsuboi, Nobushige, Hayashi, Keiichiro, Matsui, Hideki, Kurozumi, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847480/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.261
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