DDIS-01. NEW DRUG DISCOVERY WITH DRUG RE-POSITIONING SYSTEM TOWARD GBM TREATMENT

INTRODUCTION: Invasion of Glioblastoma (GBM) cells into normal brain is the major cause of poor prognosis and requires dynamic reorganization of the actin cytoskeleton, which includes lamellipodial protrusions, focal adhesions, and stress fibers at the leading edge of GBM cells. Therefore, we hypoth...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Michiue, Hiroyuki, Tsuboi, Nobushige, Hayashi, Keiichiro, Matsui, Hideki, Kurozumi, Kazuhiko
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Drug Discovery
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847480/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.261
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