TMIC-49. POTASSIUM CHANNEL KIR4.1 AND GLUTAMINE SYNTHETASE ARE DYSREGULATED IN GLIOMA

The potassium channel KIR4.1 (KCNJ10) and the glutamate catalyzing enzyme glutamine synthetase (GS) are highly expressed in glial cells of the central nervous system. Both glial proteins play important roles in the maintenance of neuronal activity and neurotransmission. Dysfunction of both proteins...

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Publicado en:Neuro Oncol
Main Authors: Schirmer, Lucas, Liesche, Friederike, Barz, Melanie, Bette, Stefanie, Wiestler, Benedikt, Srivastava, Rajneesh, Zimmer, Claus, Ringel, Florian, Rowitch, David, Meyer, Bernhard, Hemmer, Bernhard, Schlegel, Jürgen, Gempt, Jens
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Abstracts
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693154/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1037
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