TMIC-49. POTASSIUM CHANNEL KIR4.1 AND GLUTAMINE SYNTHETASE ARE DYSREGULATED IN GLIOMA

The potassium channel KIR4.1 (KCNJ10) and the glutamate catalyzing enzyme glutamine synthetase (GS) are highly expressed in glial cells of the central nervous system. Both glial proteins play important roles in the maintenance of neuronal activity and neurotransmission. Dysfunction of both proteins...

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Publié dans:Neuro Oncol
Auteurs principaux: Schirmer, Lucas, Liesche, Friederike, Barz, Melanie, Bette, Stefanie, Wiestler, Benedikt, Srivastava, Rajneesh, Zimmer, Claus, Ringel, Florian, Rowitch, David, Meyer, Bernhard, Hemmer, Bernhard, Schlegel, Jürgen, Gempt, Jens
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693154/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1037
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