TMIC-49. POTASSIUM CHANNEL KIR4.1 AND GLUTAMINE SYNTHETASE ARE DYSREGULATED IN GLIOMA

The potassium channel KIR4.1 (KCNJ10) and the glutamate catalyzing enzyme glutamine synthetase (GS) are highly expressed in glial cells of the central nervous system. Both glial proteins play important roles in the maintenance of neuronal activity and neurotransmission. Dysfunction of both proteins...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Schirmer, Lucas, Liesche, Friederike, Barz, Melanie, Bette, Stefanie, Wiestler, Benedikt, Srivastava, Rajneesh, Zimmer, Claus, Ringel, Florian, Rowitch, David, Meyer, Bernhard, Hemmer, Bernhard, Schlegel, Jürgen, Gempt, Jens
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693154/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1037
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