CBIO-23. CHARACTERIZATION OF BMP SYSTEM MUTATIONS IN RECURRENT PRIMARY GLIOBLASTOMA PRIMARY CELL CULTURES IN RELATION TO GLIOBLASTOMA INITIATING STEM-LIKE CELLS AND TEMOZOLOMIDE RESISTANCE

Glioblastoma multiforme (GBM) is the most prevalent and aggressive primary brain tumor. Its recurrence and rapidly acquired resistance to current therapies, including treatment with temozolomide (TMZ), results from the rapid expansion of re-emerging Glioblastoma Tumor Initiating stem cell-like Cells...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Verploegh, Iris, Venkatesan, Mani, Pierson, Tessa, Conidi, Andrea, Mulugeta, Eskeww, Lamfers, Martine, de Vrij, Jeroen, Huylebroeck, Danny, Leenstra, Sieger
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693011/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.142
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