CBIO-23. CHARACTERIZATION OF BMP SYSTEM MUTATIONS IN RECURRENT PRIMARY GLIOBLASTOMA PRIMARY CELL CULTURES IN RELATION TO GLIOBLASTOMA INITIATING STEM-LIKE CELLS AND TEMOZOLOMIDE RESISTANCE

Glioblastoma multiforme (GBM) is the most prevalent and aggressive primary brain tumor. Its recurrence and rapidly acquired resistance to current therapies, including treatment with temozolomide (TMZ), results from the rapid expansion of re-emerging Glioblastoma Tumor Initiating stem cell-like Cells...

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Publicado no:Neuro Oncol
Main Authors: Verploegh, Iris, Venkatesan, Mani, Pierson, Tessa, Conidi, Andrea, Mulugeta, Eskeww, Lamfers, Martine, de Vrij, Jeroen, Huylebroeck, Danny, Leenstra, Sieger
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693011/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.142
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