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IMMU-38. GLIOBLASTOMA-DERIVED IL-6 INDUCES IMMUNOSUPPRESSIVE PERIPHERAL MYELOID CELL PD-L1 EXPRESSION AND TUMOR PROGRESSION
INTRODUCTION: Peripheral myeloid cell PD-L1 expression has been identified as a biomarker of systemic immunosuppression and predictor of vaccine efficacy in GBM. While GBM secreted factors are known to induce an immunosuppressive myeloid phenotype, the specific cytokines regulating PD-L1 remain unid...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692960/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.496 |
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