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DDIS-20. FASN INHIBITION AS A POTENTIAL TREATMENT TO PREVENT METABOLIC ADAPTATION IN GBM

INTRODUCTION: Response to antiangiogenic therapy (ie bevacizumab) in glioblastoma is mostly transient and without proven survival benefit. Acquired resistance to antiangiogenics is felt to be substantially driven by the hypoxic microenvironment. METHODS: Tumor and matching sera from 12 patients havi...

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書誌詳細
出版年:Neuro Oncol
主要な著者: Gruslova, Aleksandra, Duque, Adolfo Diaz, Caflisch, Laura, Tiziani, Stefano, Lodi, Alessia, Brenner, Andrew
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692931/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.255
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