DDIS-20. FASN INHIBITION AS A POTENTIAL TREATMENT TO PREVENT METABOLIC ADAPTATION IN GBM

INTRODUCTION: Response to antiangiogenic therapy (ie bevacizumab) in glioblastoma is mostly transient and without proven survival benefit. Acquired resistance to antiangiogenics is felt to be substantially driven by the hypoxic microenvironment. METHODS: Tumor and matching sera from 12 patients havi...

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Publicado no:Neuro Oncol
Main Authors: Gruslova, Aleksandra, Duque, Adolfo Diaz, Caflisch, Laura, Tiziani, Stefano, Lodi, Alessia, Brenner, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692931/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.255
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