DDIS-20. FASN INHIBITION AS A POTENTIAL TREATMENT TO PREVENT METABOLIC ADAPTATION IN GBM

INTRODUCTION: Response to antiangiogenic therapy (ie bevacizumab) in glioblastoma is mostly transient and without proven survival benefit. Acquired resistance to antiangiogenics is felt to be substantially driven by the hypoxic microenvironment. METHODS: Tumor and matching sera from 12 patients havi...

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Vydáno v:Neuro Oncol
Hlavní autoři: Gruslova, Aleksandra, Duque, Adolfo Diaz, Caflisch, Laura, Tiziani, Stefano, Lodi, Alessia, Brenner, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692931/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.255
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