Loading...
AT-12 PHASE 1/2 STUDY OF TH-302, INVESTIGATIONAL HYPOXIA-ACTIVATED PRODRUG, AND BEVACIZUMAB IN PATIENTS WITH BEVACIZUMAB-REFRACTORY RECURRENT GLIOBLASTOMA
BACKGROUND: Hypoxia is implicated in the pathogenesis of glioblastoma multiforme (GBM), and greater hypoxic burden is associated with poorer outcomes in GBM. Treatment with bevacizumab (BEV) may increase intratumoral hypoxia. An ongoing phase 1/2 study (NCT01403610) investigates safety and activity...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2014
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217789/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou237.12 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|