CSIG-22. A CD133-Akt-Wnt SIGNALING AXIS PROVIDES FUNCTIONAL INSIGHT INTO THE ROLE OF CD133 IN GLIOBLASTOMA BRAIN TUMOR-INITIATING CELLS

Current transcriptional profiles of adult glioblastoma (GBM) recognize the activation of distinct signaling programs. Single-cell sequencing efforts have provided greater resolution of core developmental pathways implicated in disease progression and relapse. Of note, the Wnt pathway is activated in...

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Pubblicato in:Neuro Oncol
Autori principali: Manoranjan, Branavan, Venugopal, Chitra, Mahendram, Sujeivan, Subapanditha, Minomi, Savage, Neil, Qazi, Maleeha, Vora, Parvez, Moffat, Jason, Doble, Bradley, Singh, Sheila
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692788/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.216
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