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SC-33 POLYCOMB GROUP PROTEIN Bmi1 CONTROLS NEURAL STEM AND PROGENITOR CELL MAINTENANCE AND GLIOBLASTOMA TUMOUR DEVELOPMENT

Bmi1, a polycomb group protein is required for self-renewal of neural stem and progenitor cells (NSPCs). Elevated Bmi1 expression is observed in most brain tumours, including glioblastoma (GBM). GBM, one of the most aggressive and heterogeneous tumours is known to possess a subpopulation of brain tu...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Vora, Parvez, Venugopal, Chitra, Qazi, Maleeha, Mahendram, Sujeivan, McFarlane, Nicole, Singh, Sheila
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218593/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou275.32
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