TMIC-03. ONCOLYTIC VIRAL THERAPY WITH DELTA24-RGD INDUCES A TUMOR-DETRIMENTAL ENVIRONMENT VIA PHENOTYPIC SHIFT OF MACROPHAGES

INTRODUCTION: Macrophages are reported to play an important role in pathogenesis and progression of glioblastoma (GBM). Indeed, the immunosuppressive and pro-tumorous M2-macrophage is abundantly present in these tumors. Current therapeutic options for GBM only minimally improve the dismal prognosis...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: van den Bossche, Wouter, Kleijn, Anne, Teunissen, Charlotte, Voerman, Jane, Noske, David, van Dongen, Jacques, Dirven, Clemens, Lamfers, Martine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692734/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.993
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