EXTH-03. LOCAL ONCOLYTIC ADENOVIRUS TREATMENT AFFECTS BOTH THE INNATE AND ADAPTIVE ARMS OF THE IMMUNE SYSTEM AND PROVIDES AN AVENUE FOR ENHANCING IMMUNOTHERAPIES FOR GBM

The oncolytic adenovirus (OV) Delta24-RGD, also known as DNX-2401, is currently under clinical investigation for GBM. We studied multiple components of the immune system in response to local treatment with this agent using both in vitro and in vivo models and patient-derived materials. METHODS: C57B...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Lamfers, Martine, Belcaid, Zineb, van, Wouter, den Bossche, Kleijn, Anne, Berrevoets, Cor, Lamers, Cor, Teunissen, Charlotte, Noske, David, Lim, Michael, Sleijfer, Stefan, Debets, Reno, van Dongen, Jacques, Dirven, Clemens
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216934/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.352
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