PDCT-05. MOLECULAR DIAGNOSTICS REVEAL 60% HIGHER SURVIVAL FOR MOLECULARLY-VERIFIED VERSUS HISTOPATHOLOGICALLY-DIAGNOSED PEDIATRIC SUPRATENTORIAL CENTRAL NERVOUS SYSTEM EMBRYONAL TUMORS AND PINEOBLASTOMAS; A REPORT FROM THE CHILDREN’S ONCOLOGY GROUP ACNS0332 TRIAL

BACKGROUND: Children with high-risk medulloblastoma, supratentorial primitive neuroectodermal tumors (CNS-PNETs) and pineoblastomas (PBLs) have had poor survival despite intensive treatment. The Children’s Oncology Group trial ACNS0332 evaluated the efficacy of adding carboplatin or isotretinoin to...

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Publié dans:Neuro Oncol
Auteurs principaux: Hwang, Eugene, Kool, Marcel, Burger, Peter, Capper, David, Chavez, Lukas, Brabetz, Sebastian, Williams-Hughes, Chris, Billups, Catherine, Heier, Linda, Jaju, Alok, Michalski, Jeff, Li, Yimei, Zhou, Tianni, Leary, Sarah, Heideman, Nancy, von Deimling, Andreas, Jones, David, Gajjar, Amar, Packer, Roger, Pfister, Stefan M, Olson, James
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692459/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.749
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