EXTH-09. TDP1/TOP1 RATIO AS A PREDICTIVE INDICATOR FOR THE RESPONSE OF GLIOBLASTOMA CANCER CELLS TO IRINOTECAN TREATMENT

In order to make cancer chemotherapy more specific for individual patients, it would be valuable to find the predictive indicators which provide the information on cancer cell response to specific chemotherapeutic drug treatments. Topoisomerase I (TOP1) is an essential enzyme that modulates the topo...

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Vydáno v:Neuro Oncol
Hlavní autoři: Wang, Wenjie, Silva, Monica Rodriguez, Chambers, Jeremy, Tse-Dinh, Yuk-Ching
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692280/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.305
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