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RARE-31. DUAL BRAF/MEK THERAPY FOR PATIENTS WITH BRAF V600E-MUTATED TUMORS: DRAMATIC CLINICAL AND RADIOGRAPHIC RESPONSES AND A REDUCTION IN CUTANEOUS TOXICITY
INTRODUCTION: The BRAF V600E mutation is a common oncogenic driver present in a variety of primary brain tumors including pleomorphic xanthoastrocytoma (66%), pilocytic astrocytoma (9%), primary and secondary glioblastoma (2% and 6%), giant cell glioblastoma (7%), ganglioglioma (18%) and papillary c...
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Publicado no: | Neuro Oncol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692242/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.875 |
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