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RARE-31. DUAL BRAF/MEK THERAPY FOR PATIENTS WITH BRAF V600E-MUTATED TUMORS: DRAMATIC CLINICAL AND RADIOGRAPHIC RESPONSES AND A REDUCTION IN CUTANEOUS TOXICITY

INTRODUCTION: The BRAF V600E mutation is a common oncogenic driver present in a variety of primary brain tumors including pleomorphic xanthoastrocytoma (66%), pilocytic astrocytoma (9%), primary and secondary glioblastoma (2% and 6%), giant cell glioblastoma (7%), ganglioglioma (18%) and papillary c...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Bernstein, Aaron, Mrowczynski, Oliver, Khalsa, Amrit, Ryan, Sandra, Chung, Catherine, Glantz, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692242/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.875
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