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BRAF-V600E mutant papillary craniopharyngioma dramatically responds to combination BRAF and MEK inhibitors
We present a patient with BRAF-V600E mutant papillary craniopharyngioma successfully treated with combination BRAF (dabrafenib 150 mg twice daily) and MEK (trametinib 2 mg daily) inhibitors after her unresectable tumor proved refractory to radiation. Serial brain MRIs and PET revealed marked tumor r...
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| Udgivet i: | CNS Oncol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Future Medicine Ltd
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6020871/ https://ncbi.nlm.nih.gov/pubmed/28425764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns-2016-0034 |
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