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BRAF-V600E mutant papillary craniopharyngioma dramatically responds to combination BRAF and MEK inhibitors

We present a patient with BRAF-V600E mutant papillary craniopharyngioma successfully treated with combination BRAF (dabrafenib 150 mg twice daily) and MEK (trametinib 2 mg daily) inhibitors after her unresectable tumor proved refractory to radiation. Serial brain MRIs and PET revealed marked tumor r...

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Dades bibliogràfiques
Publicat a:CNS Oncol
Autors principals: Roque, Ashley, Odia, Yazmin
Format: Artigo
Idioma:Inglês
Publicat: Future Medicine Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020871/
https://ncbi.nlm.nih.gov/pubmed/28425764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns-2016-0034
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