Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy

We recently reported that BRAF V600E is the principal oncogenic driver of papillary craniopharyngioma, a highly morbid intracranial tumor commonly refractory to treatment. Here, we describe our treatment of a man age 39 years with multiply recurrent BRAF V600E craniopharyngioma using dabrafenib (150...

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Sparad:
Bibliografiska uppgifter
I publikationen:J Natl Cancer Inst
Huvudupphovsmän: Brastianos, Priscilla K., Shankar, Ganesh M., Gill, Corey M., Taylor-Weiner, Amaro, Nayyar, Naema, Panka, David J., Sullivan, Ryan J., Frederick, Dennie T., Abedalthagafi, Malak, Jones, Pamela S., Dunn, Ian F., Nahed, Brian V., Romero, Javier M., Louis, David N., Getz, Gad, Cahill, Daniel P., Santagata, Sandro, Curry, William T., Barker, Fred G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Brief Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862417/
https://ncbi.nlm.nih.gov/pubmed/26498373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv310
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