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Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy
We recently reported that BRAF V600E is the principal oncogenic driver of papillary craniopharyngioma, a highly morbid intracranial tumor commonly refractory to treatment. Here, we describe our treatment of a man age 39 years with multiply recurrent BRAF V600E craniopharyngioma using dabrafenib (150...
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| Veröffentlicht in: | J Natl Cancer Inst |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862417/ https://ncbi.nlm.nih.gov/pubmed/26498373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv310 |
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