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IMMU-09. DISRUPTION OF THE CCL2-CCR2 AXIS AUGMENTS THE EFFECTS OF IMMUNE CHECKPOINT INHIBITORS TO SLOW PROGRESSION OF GLIOMAS

INTRODUCTION: Therapeutic approaches that target the immune system in cancer are gaining traction, with agents that disrupt the PD-L1/PD-1 axis showing success in melanoma and lung cancers. Pre-clinical and early clinical studies also indicate that these immune checkpoint inhibitors have efficacy in...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Gopinath, Adithya, Luo, Defang, Sarkisian, Matthew, Campbell, James, Charo, Israel, Schall, Thomas, Harrison, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692106/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.468
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