CSIG-12. EXPLORING THE FUNCTIONAL RELATIONSHIP BETWEEN CAPICUA (CIC) AND ATAXIN-1-LIKE (ATXN1L) IN GLIOMA

BACKGROUND: Oligodendroglioma (ODG), a molecularly defined subtype of glioma, is a treatment responsive, slow growing tumour strongly associated with IDH mutation and 1p19q co-deletion. Mutations in CIC, located on chromosome 19q, have been found in up to 70% of IDH mutated, 1p19q co-deleted ODGs; s...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Wong, Derek, Lounsbury, Kohl, LeBlanc, Veronique, Chittaranjan, Suganthi, Marra, Marco, Yip, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692065/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.207
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