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EXTH-36. DEVELOPMENT OF STABLE AND BRAIN-PENETRATING DISULFIRAM NANOPARTICLES, CHARACTERIZATION AND EFFICACY IN GLIOMA CELL CULTURE AND XENOGRAFT MODELS

Blood brain-barrier entry, tumor heterogeneity, need to eliminate the tumorigenic stem cells and inhibit the DNA repair protein MGMT are all essential considerations in glioma treatment. Previously, we showed that alcohol aversion drug disulfiram (DSF) shares all these properties [Carcinogenesis 35,...

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Madala, Hanumantha Rao, Punganuru, Surendra Reddy, Srivenugopal, Kalkunte, Ali-Osman, Francis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692037/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.328
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