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Human DNA replication initiation factors, ORC and MCM, associate with oriP of Epstein–Barr virus

The 165-kb chromosome of Epstein–Barr virus (EBV) is replicated by cellular enzymes only once per cell cycle in human cells that are latently infected. Here, we report that the human origin recognition complex, ORC, can be detected in association with an EBV replication origin, oriP, in cells by usi...

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Detalhes bibliográficos
Main Authors: Chaudhuri, Biswendu, Xu, Hongzhan, Todorov, Ivan, Dutta, Anindya, Yates, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC56919/
https://ncbi.nlm.nih.gov/pubmed/11517328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181347998
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