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Human DNA replication initiation factors, ORC and MCM, associate with oriP of Epstein–Barr virus

The 165-kb chromosome of Epstein–Barr virus (EBV) is replicated by cellular enzymes only once per cell cycle in human cells that are latently infected. Here, we report that the human origin recognition complex, ORC, can be detected in association with an EBV replication origin, oriP, in cells by usi...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Chaudhuri, Biswendu, Xu, Hongzhan, Todorov, Ivan, Dutta, Anindya, Yates, John L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2001
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC56919/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11517328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.181347998
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