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Sequences Adjacent to oriP Improve the Persistence of Epstein-Barr Virus-Based Episomes in B Cells

Epstein-Barr virus (EBV) oriP and the EBV nuclear antigen 1 (EBNA-1) protein allow persistence of EBV-based episomes. A nuclear matrix attachment region (MAR) spans oriP and the adjacent region of the EBV genome containing the EBV-expressed RNAs. Here, we show that episomes with the MAR are retained...

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Autores principales: White, Robert E., Wade-Martins, Richard, James, Michael R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC114707/
https://ncbi.nlm.nih.gov/pubmed/11602767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.11249-11252.2001
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