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Why multiple small subunits (Y2 and Y4) for yeast ribonucleotide reductase? Toward understanding the role of Y4

Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to deoxynucleotides. Class I RNRs are composed of two homodimeric subunits: R1 and R2. R1 is directly involved in the reduction, and R2 contains the diferric-tyrosyl radical (Y⋅) cofactor essential for the initiation of reductio...

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Autors principals: Ge, Jie, Perlstein, Deborah L., Nguyen, Hiep-Hoa, Bar, Galit, Griffin, Robert G., Stubbe, JoAnne
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC56916/
https://ncbi.nlm.nih.gov/pubmed/11526232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181336498
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