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Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment

There is evidence both for and against Na(+)- and Cl(−)-dependent neurotransmitter transporters forming oligomers. We found that cross-linking the human dopamine transporter (DAT), which is heterologously expressed in human embryonic kidney 293 cells, either with copper phenanthroline (CuP) or the b...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Hastrup, Hanne, Karlin, Arthur, Javitch, Jonathan A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC56914/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11526230/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.181344298
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