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Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment

There is evidence both for and against Na(+)- and Cl(−)-dependent neurotransmitter transporters forming oligomers. We found that cross-linking the human dopamine transporter (DAT), which is heterologously expressed in human embryonic kidney 293 cells, either with copper phenanthroline (CuP) or the b...

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Detalhes bibliográficos
Main Authors: Hastrup, Hanne, Karlin, Arthur, Javitch, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC56914/
https://ncbi.nlm.nih.gov/pubmed/11526230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181344298
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