The Molecular Tweezer CLR01 Stabilizes a Disordered Protein–Protein Interface

[Image: see text] Protein regions that are involved in protein–protein interactions (PPIs) very often display a high degree of intrinsic disorder, which is reduced during the recognition process. A prime example is binding of the rigid 14-3-3 adapter proteins to their numerous partner proteins, whos...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Bier, David, Mittal, Sumit, Bravo-Rodriguez, Kenny, Sowislok, Andrea, Guillory, Xavier, Briels, Jeroen, Heid, Christian, Bartel, Maria, Wettig, Burkhard, Brunsveld, Luc, Sanchez-Garcia, Elsa, Schrader, Thomas, Ottmann, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691318/
https://ncbi.nlm.nih.gov/pubmed/29039919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07939
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