TOP2A and EZH2 provide early detection of an aggressive prostate cancer subgroup

PURPOSE: Current clinical parameters do not stratify indolent from aggressive prostate cancer (PCa). Aggressive PCa, defined by the progression from localized disease to metastasis, is responsible for the majority of PCa-associated mortality. Recent gene expression profiling has proven successful in...

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Pubblicato in:Clin Cancer Res
Autori principali: Labbé, David P., Sweeney, Christopher J., Brown, Myles, Galbo, Phillip, Rosario, Spencer, Wadosky, Kristine M., Ku, Sheng-Yu, Sjöström, Martin, Alshalalfa, Mohammed, Erho, Nicholas, Davicioni, Elai, Karnes, R. Jeffrey, Schaeffer, Edward M., Jenkins, Robert B., Den, Robert B., Ross, Ashley E., Bowden, Michaela, Huang, Ying, Gray, Kathryn P., Feng, Felix Y., Spratt, Daniel E., Goodrich, David W., Eng, Kevin H., Ellis, Leigh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690819/
https://ncbi.nlm.nih.gov/pubmed/28899973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0413
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