Halofuginone inhibits TGF-β/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis

More efficient therapies that target multiple molecular mechanisms are needed for the treatment of incurable bone metastases. Halofuginone is a plant alkaloid-derivative with antiangiogenic and antiproliferative effects. Here we demonstrate that halofuginone is an effective therapy for the treatment...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Juárez, Patricia, Fournier, Pierrick G.J., Mohammad, Khalid S., McKenna, Ryan C., Davis, Holly W., Peng, Xiang H., Niewolna, Maria, Mauviel, Alain, Chirgwin, John M., Guise, Theresa A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2017
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689697/
https://ncbi.nlm.nih.gov/pubmed/29156807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21200
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