The TGFβ Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

Transforming growth factor-β (TGFβ) regulates the expression of genes supporting breast cancer cell in bone but little is known about prostate cancer bone metastases and TGFβ. Our study reveals that the TGFBR1 inhibitor SD208 effectively reduces prostate cancer bone metastases. TGFβ upregulates in p...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Fournier, Pierrick GJ., Juárez, Patricia, Jiang, Guanglong, Clines, Gregory A., Niewolna, Maria, Kim, Hun Soo, Walton, Holly W., Peng, C. Xiang Hong, Liu, Yunlong, Mohammad, Khalid S., Wells, Clark D., Chirgwin, John M., Guise, Theresa A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464909/
https://ncbi.nlm.nih.gov/pubmed/25982816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.04.009
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