Asiatic acid protects against hepatic ischemia/reperfusion injury by inactivation of Kupffer cells via PPARγ/NLRP3 inflammasome signaling pathway

Hepatic ischemia/reperfusion (I/R) contributes to major complications in clinical practice affecting perioperative morbidity and mortality. Recent evidence suggests the key role of nucleotide-binding oligomerization domain-like receptor (NLR) family pyrin domain-containing 3 (NLRP3) inflammaosme act...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xu, Ying, Yao, Jun, Zou, Chen, Zhang, Heng, Zhang, Shouliang, Liu, Jun, Ma, Gui, Jiang, Pengcheng, Zhang, Wenbo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689689/
https://ncbi.nlm.nih.gov/pubmed/29156799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21151
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