Methylation of microRNA-129-5P modulates nucleus pulposus cell autophagy by targeting Beclin-1 in intervertebral disc degeneration

MicroRNAs play an important role in the etiology and progression of many diseases, including intervertebral disc degeneration (IVDD). The miRNA miR-129-5P regulates autophagy in various cancers, but its role in human nucleus pulposus (NP) cells is unclear. The present study investigated whether miR-...

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Pubblicato in:Oncotarget
Autori principali: Zhao, Kangcheng, Zhang, Yukun, Kang, Liang, Song, Yu, Wang, Kun, Li, Shuai, Wu, Xinghuo, Hua, Wenbin, Shao, Zengwu, Yang, Shuhua, Yang, Cao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689683/
https://ncbi.nlm.nih.gov/pubmed/29156793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21137
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