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Activation of IGF-1 Receptors and Akt signaling by systemic hyperinsulinemia contributes to cardiac hypertrophy but does not regulate cardiac autophagy in obese diabetic mice
Autophagy plays an important role in the maintenance of normal heart function. However, the role of autophagy in the inulin resistant and diabetic heart is not well understood. Furthermore, the upstream signaling and the downstream targets involved in cardiac autophagy regulation during obesity and...
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| 出版年: | J Mol Cell Cardiol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5689477/ https://ncbi.nlm.nih.gov/pubmed/28987875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.10.001 |
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