Recurrent activating mutations of CD28 in peripheral T-cell lymphomas

Peripheral T-cell lymphomas (PTCLs) comprise a heterogeneous group of mature T-cell neoplasms with a poor prognosis. Recently, mutations in TET2 and other epigenetic modifiers as well as RHOA have been identified in these diseases, particularly in angioimmunoblastic T-cell lymphoma (AITL). CD28 is t...

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Publicat a:Leukemia
Autors principals: Rohr, Joseph, Guo, Shuangping, Huo, Jiandong, Bouska, Alyssa, Lachel, Cynthia, Li, Yuping, Simone, Peter D., Zhang, Weiwei, Gong, Qiang, Wang, Chao, Cannon, Andrew, Heavican, Tayla, Mottok, Anja, Hung, Stacy, Rosenwald, Andreas, Gascoyne, Randy, Fu, Kai, Greiner, Timothy C., Weisenburger, Dennis D., Vose, Julie M., Staudt, Louis M., Xiao, Wenming, Borgstahl, Gloria E. O., Davis, Simon, Steidl, Christian, McKeithan, Timothy, Iqbal, Javeed, Chan, Wing C.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688878/
https://ncbi.nlm.nih.gov/pubmed/26719098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.357
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