IDH2(R172) mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma

Angioimmunoblastic T-cell lymphoma (AITL) is a common subtype of peripheral T-cell lymphoma (PTCL) with a poor prognosis. We performed targeted resequencing on 92 cases of PTCL and identified frequent mutations affecting RHOA, TET2, DNMT3A, and isocitrate dehydrogenase 2 (IDH2). Although IDH2 mutati...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Wang, Chao, McKeithan, Timothy W., Gong, Qiang, Zhang, Weiwei, Bouska, Alyssa, Rosenwald, Andreas, Gascoyne, Randy D., Wu, Xiwei, Wang, Jinhui, Muhammad, Zahid, Jiang, Bei, Rohr, Joseph, Cannon, Andrew, Steidl, Christian, Fu, Kai, Li, Yuping, Hung, Stacy, Weisenburger, Dennis D., Greiner, Timothy C., Smith, Lynette, Ott, German, Rogan, Eleanor G., Staudt, Louis M., Vose, Julie, Iqbal, Javeed, Chan, Wing C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Plenary Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600014/
https://ncbi.nlm.nih.gov/pubmed/26268241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-644591
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