IDH2(R172) mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma

Angioimmunoblastic T-cell lymphoma (AITL) is a common subtype of peripheral T-cell lymphoma (PTCL) with a poor prognosis. We performed targeted resequencing on 92 cases of PTCL and identified frequent mutations affecting RHOA, TET2, DNMT3A, and isocitrate dehydrogenase 2 (IDH2). Although IDH2 mutati...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Wang, Chao, McKeithan, Timothy W., Gong, Qiang, Zhang, Weiwei, Bouska, Alyssa, Rosenwald, Andreas, Gascoyne, Randy D., Wu, Xiwei, Wang, Jinhui, Muhammad, Zahid, Jiang, Bei, Rohr, Joseph, Cannon, Andrew, Steidl, Christian, Fu, Kai, Li, Yuping, Hung, Stacy, Weisenburger, Dennis D., Greiner, Timothy C., Smith, Lynette, Ott, German, Rogan, Eleanor G., Staudt, Louis M., Vose, Julie, Iqbal, Javeed, Chan, Wing C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2015
Soggetti:
Plenary Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600014/
https://ncbi.nlm.nih.gov/pubmed/26268241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-644591
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